Advanced Radioligand Therapy with Lutetium PSMA
Lutetium PSMA therapy is a highly specialised treatment designed for men with advanced prostate cancer. It combines a radioactive substance (Lutetium-177) with a molecule that seeks out PSMA, a protein commonly found on prostate cancer cells. This allows radiation to be delivered directly to the tumour while minimising damage to healthy tissues. Dr Carla Perna offers this cutting-edge therapy to suitable patients, using her expertise to guide each step from assessment to ongoing care, helping extend survival and improve quality of life.
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How Lutetium PSMA Therapy Targets Prostate Cancer
Lutetium PSMA therapy works as a "smart" form of radiotherapy. The treatment uses a compound that attaches to PSMA, a marker on most prostate cancer cells, carrying targeted radiation straight to the tumour. This approach is beneficial for men with advanced or metastatic disease that no longer responds to standard hormone therapy. Dr Carla Perna evaluates each patient through specialised imaging and clinical assessment to ensure the treatment is appropriate. She also monitors response closely, managing side effects like mild fatigue or dry mouth to keep the experience as smooth as possible. Her goal is to offer cutting-edge therapy with personalised, compassionate care.
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My consultation with Dr Perna was very proficient and professional. She explained my condition well and has arranged for further tests to be carried out to determine the best and appropriate way forward. Would certainly recomend Dr Perna to other individuals.

My consultation with Dr Perna was very proficient and professional. She explained my condition well and has arranged for further tests to be carried out to determine the best and appropriate way forward. Would certainly recomend Dr Perna to other individuals.

My consultation with Dr Perna was very proficient and professional. She explained my condition well and has arranged for further tests to be carried out to determine the best and appropriate way forward. Would certainly recomend Dr Perna to other individuals.

Your Lutetium PSMA questions, answered.
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What is Lutetium-177 PSMA therapy?
Lutetium-177 PSMA therapy is a form of targeted radioligand treatment. It combines a radioactive particle (Lutetium-177) with a molecule that attaches to PSMA, a protein found on most prostate cancer cells. This allows radiation to be delivered directly to the cancer, while limiting damage to surrounding healthy tissues. Dr Carla Perna offers this advanced treatment specifically for men with prostate cancer, particularly those with disease that has spread or no longer responds to standard hormone therapy.
How is Lutetium PSMA therapy given?
The treatment is delivered through a small intravenous (IV) infusion, usually as an outpatient procedure. Patients typically receive several cycles spaced a few weeks apart. Before starting, a special scan confirms that the cancer cells show enough PSMA for the therapy to work. Dr Carla Perna administers Lutetium PSMA therapy only for prostate cancer, carefully monitoring patients during and after each session to ensure safety and track response.
Who is eligible for Lutetium PSMA therapy?
Lutetium PSMA therapy is usually offered to men with advanced or metastatic prostate cancer that has stopped responding to standard hormone therapy. A PSMA PET scan is needed to confirm that the cancer has enough PSMA receptors for the treatment to work effectively. Dr Carla Perna evaluates eligibility carefully for her prostate cancer patients, reviewing scans, blood tests, and overall health to ensure this therapy is the right option.
What are the side effects of Lutetium PSMA therapy?
Most people tolerate this treatment well, but mild side effects can include fatigue, nausea, dry mouth, or temporary changes in blood counts. Some patients may notice mild pain where tumours are shrinking. Dr Carla Perna supports her prostate cancer patients throughout treatment, monitoring for side effects and providing early management to keep therapy as comfortable and safe as possible.
How effective is Lutetium PSMA therapy for advanced prostate cancer?
Lutetium PSMA therapy has shown impressive results in controlling advanced prostate cancer, helping shrink tumours, reduce PSA levels, relieve pain, and extend survival when other treatments have stopped working. Dr Carla Perna offers this therapy specifically to men with prostate cancer, using careful patient selection and personalised follow-up to maximise its benefits while maintaining quality of life.